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KMID : 0043319970200060597
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Archives of Pharmacal Research
1997 Volume.20 No. 6 p.597 ~ p.601
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2,3-Dichloro-5,6-Dicyano-1,4-Benzoquinone As a Redox Titrant
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El-Brash A.M.
El-Hussain Laila A.
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Abstract
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An oxidimetric titrant, 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone in anhydrous acetic acid is used for the semimicro-determination of hydrazine hydrate, phenylhydrazine hydrochloride, isoniazid and iproniazid phosphate in pure forms as well as in some pharmaceutical preparations containing isoniazid and iproniazid phosphate. The end point was detected potentiometrically using a platinum-calomel combination electrode. The results obtained are compared statistically with those obtained by the official methods and they are in good agreement.
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KEYWORD
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2,4-Dichloro-5,6, dicyano-1,4-benzoquinone, Hydrazine hydrate, Phenylhydrazine hydrochloride, Isoniazid, lproniazid, phosphate Titrimetry, Dosage forms
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